The shooter — identified by media as a 46-year-old white man — reportedly yelled anti-Jewish slurs as he launched the attack at the Tree of Life synagogue during a baby naming ceremony.
The suspect was taken into police custody and transferred to hospital.
Dozens of people were gathered during Sabbath services at the time of the attack, which federal investigators were treating as a hate crime.
As police cars, ambulances and a SWAT team surrounded the synagogue in the historically Jewish neighborhood of Squirrel Hill, Wendell Hissrich, Pittsburgh’s public safety director, confirmed “multiple fatalities” and at least six people injured including four police officers whose condition was not immediately clear.
TheWashington Postand the localCBSaffiliate said 11 people were dead.
“The scene is very bad inside,” Hissrich said. “It’s a very horrific crime scene, one of the worst that I’ve seen, I’ve been on plane crashes. It’s very bad.”